The plant is native to China, so kudzu root has a long history in Chinese medicine. By considering these factors, you can choose the best anti-alcohol supplement for your needs. Remember to always consult with a healthcare professional before starting any new supplement regimen.

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Therefore, it could be used as an aversion therapy for alcohol use disorder 40. It is the only natural medication regarded by the National Institute on Alcohol Abuse and Alcoholism to treat alcohol use disorder 44. In a clinical population study, kudzu treatment resulted in significant reduction in alcohol intake in a naturalistic setting. The number of beers consumed and the volume of each sip was decreased while the number of sips and the time to consume each beer was increased.

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Natural products for the prevention and treatment of hangover and what is alcoholism alcohol use disorder. The main bioactive components of Scutellaria baicalensis are baicalein, baicalin and wogonin. Baicalein at the concentrations of 40–120 μM exerted cytotoxicity to three hepatocellular carcinoma cell lines but with little cytotoxicity to a normal liver cell line in vitro 124. In addition, baicalin has potential beneficial effects on ischemia/reperfusion (I/R) injury in alcoholic fatty liver.

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Ultimately, a comprehensive approach to health and well-being, including evidence-based treatments, remains paramount. Antioxidants help neutralize these molecules, reducing the risk of oxidative stress and related health problems. This is because isoflavones can help dilate blood vessels, allowing for better blood flow. Kudzu may also help reduce the risk of blood clots, which can lead kudzu for alcohol cravings to heart attacks and strokes.

• Hypericum perforatum and Salvia miltiorrhiza could be potential natural products to treat alcohol use disorder and will be discussed below, while Scutellaria baicalensis is important in the treatment of liver disease.
• Using the continuous measure of alcohol consumption, drinking was quantified using a number of different variables as noted above.
• Scientists need to do more research to investigate the potential of kudzu root to cause liver injury in humans.
• Cravings are often linked to the rewarding effects of alcohol, so kudzu’s ability to change the dopamine system can impact cravings and their intensity.
• It works by enhancing the effects of GABA, a neurotransmitter that plays a critical role in calming the nervous system.

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In addition, the flowers of kudzu exerted protective effects against alcohol-induced apoptosis in human neuroblastoma cells 43. In cases of alcoholism, the doses studied in scientific research were 1.5-3g of kudzu root extract taken in 3 doses per day over 1-4 weeks. A single dose of 2g of kudzu extract has also been used in other studies before a drinking session.

• While scientists need to do more research on the health effects of kudzu, some studies suggest that kudzu root may have other health benefits worth considering.
• Asian ginseng (Panax ginseng) has therapeutic potential for the treatment of alcohol toxicity and as an anti-hangover agent.
• However, more research is needed to determine its long-term effectiveness in promoting alcoholism recovery.
• Disulfiram is a pill that causes unpleasant side effects when combined with alcohol.

Although scientific evidence demonstrates the efficacy of kudzu for quitting drinking or smoking, results in wider populations still need to be confirmed. Kudzu works somewhat similarly to acamprosate in many ways, but since it is an approved prescription medication, there’s more clinical evidence to show the benefits of acamprosate. Some people have a genetic predisposition to becoming dependent on alcohol and may be more vulnerable to the reinforcing effects it can have. Always consult a healthcare professional before using Kudzu to ensure it is safe and appropriate for your individual needs. People who are pregnant, breastfeeding, or taking medications, especially for hormone-related or cardiovascular conditions, should avoid consuming Kudzu without medical advice. While more research is needed, kudzu’s long history in traditional medicine speaks to its safety and value.

After the intervention of FPEt in cells, the expression of ADH, ALDH, and CYP2E1 were upregulated, whereas the expression of cytochrome-c was downregulated in the alcohol-treated cells. Increased hepatocyte viability and reduced apoptotic nuclei were observed in FPEt-treated rats 54. In addition, the expression of cellular heat shock proteins-HSP70, HSC70, HSC92, and mitochondrial protein mtHSP70 were produced in alcohol-treated Chang liver cells, which suggested a protective effect of FPEt 55. Moreover, FPEt administration had a positive influence on both lipid profile and collagen properties in alcoholic liver disease. Treatment of alcohol-fed rats (200 mg/kg/day) with FPEt significantly reduced the levels of lipid peroxidation products and protein carbonyl content, as well as prevented the leakage of enzymatic and lipid peroxidation rise 56.

It contains several active isoflavones, which are natural plant chemicals with antioxidant effects. When alcohol is consumed, kudzu may reduce the time it takes for it to travel to the brain. A slightly increased concentration of alcohol in the brain results in a quicker reward, which in turn reduces a person’s desire to drink more alcohol. Moreover, kudzu has been investigated for its effects on the brain’s reward system.